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In 1848, a railroad worker survived an accident that drove a 13-pound iron bar through his head. The injury changed his personality, and our understanding of the brain.

General Manuel Noriega, who was de facto leader of Panama before his ouster by U.S. troops in 1989, has died. Noreiga was brought to the U.S. where he was tried and imprisoned for drug trafficking.

In New York City, the venerable Hudson Theater reopens this week, after nearly a half-century of being used for other purposes. It's the newest addition to Broadway's 40 stages.

Leave it to the Italians to take a holiday steeped in women's rights and turn it into Festa Della Donna, when women leave menfolk behind to celebrate each other with flowers, wine and above all, cake.

In upcoming congressional fights, a group of senators are highly sought by the White House for support. They are Democrats who are up for re-election in 2018 in states that Donald Trump won in 2016.

In Vice President Pence's hometown of Columbus, Ind., there are a lot immigrants with H-1B visas who were affected by the on-hold executive order. Others are scared they could be next.

The Conservative Political Action Conference will hear from Donald Trump Friday. We discuss how Trump's idea of "America first" squares with traditional Republican ideas.

It's easy for a humanitarian group to go into a country with ambitious goals. It's tougher to figure out how to walk away.

Is trade school the ticket? Does the middle class have the worst debt woes? Listeners weigh in with burning student loan questions.

President Trump campaigned on fighting the opioid crisis. Now a preliminary White House budget document, obtained by NPR, calls for significant cuts to the office quarterbacking the federal response.